Development and optimization of metoprolol succinate gastroretentive drug delivery system
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چکیده
منابع مشابه
Development and optimization of metoprolol succinate gastroretentive drug delivery system.
Metoprolol succinate (MS) gastroretentive (GR) controlled release system was formulated to increase gastric residence time leading to improved drug bioavailability. Box-Behnken model was followed using novel combinations of sodium alginate (SA), sodium carboxymethylcellulose (NaCMC), magnesium alumino metasilicate (MAS) as independent variables. Floating lag time (Flag), t25, t50, t75, diffusio...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica
سال: 2010
ISSN: 1846-9558,1330-0075
DOI: 10.2478/v10007-010-0031-x